GIANT CONGENITAL MELANOCYTIC NEVUS (BATHING TRUNK NEVUS)- A CASE STUDY
نویسندگان
چکیده
منابع مشابه
Giant congenital melanocytic nevus (bathing trunk nevus) associated with lipoma and neurofibroma: report of two cases.
Giant congenital melanocytic nevi are rare and occur in about one out of every 2,00,000 to 5,00,000 births. There is a significant association between bathing trunk nevus and neurofibromatosis and lipomatosis. Apart from this, association of bathing trunk nevus with abnormalities like spina bifida occulta, meningocele, club foot and hypertrophy or atrophy of deeper structures of a limb, have be...
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Giant congenital melanocytic nevus is usually defined as a melanocytic lesion present at birth that will reach a diameter ≥ 20 cm in adulthood. Its incidence is estimated in <1:20,000 newborns. Despite its rarity, this lesion is important because it may associate with severe complications such as malignant melanoma, affect the central nervous system (neurocutaneous melanosis), and have major ps...
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Figure 1. Two-year-old boy with a giant congenital melanocytic nevus of the left buttock. Left, Center, Preoperative views. Right, Immediate view after excision and placement of the Integra bilayer matrix dressing. Figure 2. Left, Wound after removal of the silicone layer of the Integra bilayer matrix dressing. Right, Coverage of the wound with a split skin autograft.
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Congenital melanocytic nevus syndrome (CMNS) is the result of an abnormal proliferation of melanocytes in the skin and central nervous system caused by progenitor-cell mutations during embryonic development. Mutations in the NRAS gene have been detected in many of these cells. We present 5 cases of giant congenital melanocytic nevus, 3 of them associated with CMNS; NRAS gene mutation was studie...
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ژورنال
عنوان ژورنال: Journal of Evolution of Medical and Dental Sciences
سال: 2018
ISSN: 2278-4748,2278-4802
DOI: 10.14260/jemds/2018/380